Endocrine Abstracts

Introduction: We present an interesting case of cyclical Cushing’s syndrome who became too unwell to loose her job and confidence as a result of the condition prior to diagnosis of her condition.Case report: A 44-year-old social worker referred by GP in 2007 for investigation of ‘possible hypo- or hyperadrenalism’. She had been diagnosed with polycystic ovary syndrome in 2002 (based on symptoms and ovarian ultrasound) and recently diagnose...

A thirty year old woman with complete 21-hydroxylase deficiency presented with a five centimetre adrenal mass necessitating operative removal to exclude malignant change. Her medical management had always been unsatisfactory, and she had been tried on both hydrocortisone and dexamethasone. When taking 1 milligram dexamethasone daily she had partially suppressed androgen levels, (evidenced by a fall in 17-hydroxy-progesterone levels to 29 nmol/l), at the expense of marked Cushi...